The IAPP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Amylin, IAPP, and Islet Amyloid Polypeptide. This antibody recognizes Human antigen. The IAPP Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes